Sean Dyche's Burnley take on Jose Mourinho's Tottenham Hotspur at Turf Moor in Monday Night Football from the Premier League.
Wycombe Wanderers welcome Watford to Adams Park in midweek action from the Sky Bet Championship.
Swansea City take on Stoke City at the Liberty Stadium in midweek action from the Sky Bet Championship.
Manchester City travel to Stade Vélodrome to take on Marseille in Group C of the UEFA Champions League. This is the first time the two sides have met in European competition.
Liverpool welcome Midtjylland to Anfield in Group D of the UEFA Champions League. Liverpool have lost just one of their last 26 home games in all European competitions.
Chelsea travel to Krasnodar Stadium to face Krasnodar in Group E of the UEFA Champions League. This will be Krasnodar's first ever home Champions League tie.
Luton Town take on Nottingham Forest at Kenilworth Road in the Sky Bet Championship.
Manchester United host RB Leipzig at Old Trafford in Group H of the UEFA Champions League. United are unbeaten in their last 10 home games against German sides.
Juventus host Barcelona in Group G at Juventus Stadium. This will be the first Champions League meeting between Lionel Messi and Cristiano Ronaldo since 2011.
Antwerp take on Tottenham at Bosuilstadion in Group J of the UEFA Europa League. Spurs have managed just one win from their last eight Europa League away games.
Lille host Celtic in Group H of the UEFA Europa League at Stade Pierre-Mauroy. Lille's Yusuf Yazici netted a hat-trick against Sparta Prague on matchday one.
Leicester City travel to the Athens Olympic Stadium to take on AEK Athens in Group G of the UEFA Europa League. Leicester prevailed 3-0 winners over Zorya on matchday one.
Rangers host Lech Poznan at Ibrox Stadium in Group D of the UEFA Europa League. Rangers striker Kemar Roofe scored the longest-range goal in UEFA Europa history on matchday one.
Arsenal host Dundalk at the Emirates Stadium in Group B of the UEFA Europa League. This is the first time that Arsenal will face Irish opposition in UEFA competition.
Coventry City welcome Reading to St Andrew's for a Friday evening clash from the Sky Bet Championship.
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